Mass spectrometry has been widely used in both general protein quantification and the study of protein translation modifications, making it one of the primary analytical techniques for proteome quantification. Based on whether the target protein is quantified, it can be divided into untargeted quantification and targeted quantification. Untargeted quantification can further be classified into label-free quantification and labeled […]
What is protein cross-linking? Protein crosslinking usually refers to the joining of two amino acids in a protein by a covalent bond other than a peptide bond. Protein crosslinking includes both intermolecular and intramolecular crosslinking, which are distinguished by whether the amino acids attached at the ends of the crosslink are from the same protein. […]
Introduction to Single-Cell RNA Sequencing RNA sequencing (RNA-seq) is a genomic technique for detecting and quantifying messenger RNA molecules in biological samples, which is useful for studying cellular responses. In recent years, RNA-seq has fueled a lot of medical discoveries and innovations. The approach is frequently applied to samples containing thousands to millions of cells […]